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This regulatory precaution originated in rodent toxicology studies where mice and rats developed C-cell hyperplasia and tumors
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The GLP-1 analogs, semaglutide and liraglutide, delay the progression of atherosclerosis by regulating inflammatory pathways in low-density lipoprotein receptor-deficient (LDLr -/- ) and apolipoprotein E-deficient (ApoE -/- ) mice 16
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